Somatostatin is a peptide hormone that is produced in the hypothalamus and pancreas and works to inhibit the secretion of hormones and other signaling molecules. This multi-functional hormone is also called growth hormone-inhibiting hormone, somatotropin release-inhibiting factor, or SST for short. Other common synonyms for somatostatin include growth hormone release-inhibiting hormone, somatostatin-14, or somatotropin release-inhibiting factor. It has been associated with the regulation of various physical functions such as insulin and glucagon secretion, gastrointestinal motility, and fluid balance. The understanding of somatostatin and its synonyms is essential in the field of endocrinology, as it plays a critical role in human physiology that affects overall health and well-being.