The word "most wielding" implies control, authority, and power. Several synonyms can replace this term to convey a similar meaning, such as dominant, influential, commanding, powerful, and authoritative. Other synonyms that could be used include superior, potent, formidable, overbearing, and mighty. These words all convey a sense of strength and influence. Depending on the context of the sentence, one may also choose to use words such as prevailing, effective, or significant. Ultimately, the word chosen to replace "most wielding" will depend on the tone and intended message of the sentence.