Hereditary motor and sensory neuropathy, commonly known as Charcot-Marie-Tooth (CMT) disease, is a genetic disorder that affects the peripheral nerves. The disease leads to muscle weakness and numbness in the hands and feet, and it can be inherited from one generation to the next. Synonyms for hereditary motor and sensory neuropathy include hereditary motor sensory neuropathy, hereditary neuropathy, and hereditary sensory neuropathy. Other terms for the condition are Charcot-Marie-Tooth disease, Crow-Fukase syndrome, Dejerine-Sottas syndrome, and Roussy-Levy syndrome. While there is no cure for CMT, treatments such as physiotherapy, orthotics, and surgery can help manage symptoms and improve quality of life for those affected by the disease.