There are various synonyms for the term "give best shot." Some of the synonyms include "do one's best," "put in one's maximum effort," "give it one's all," "put forth one's best foot," "work as hard as possible," "put in one's utmost," "put up one's finest effort," "give one's best performance," "exert oneself," and "give it one's full attention." All these alternate phrases convey the idea of putting in the maximum effort, striving to do one's best and achieving the best possible outcome. It is essential to give your best shot in everything that you do to achieve success and fulfilment.