Familiar

Antonyms of familiar:
unknown, uninformed, quaint, other, unacquainted, eery, queer, distant, strange, oddish, freaky, unacquainted with, rum, fantastic, singular, odd, rummy, weird, fantastical, curious, eerie, antic, funny, gothic, exotic, unfamiliar, peculiar, unusual, grotesque, crazy, unfamiliar with, remote, exceptional, infrequent, rare, uncommon, aloof, antisocial, cold, cool, detached, frosty, reserved, standoffish, unfriendly, unsociable, withdrawn, insensible, unaware, unconscious, unmindful, blind, oblivious, unknowing, unwitting, inattentive, unheeding, ignorant, unknowledgeable, aberrant, abnormal, irregular, unnatural, intermittent, occasional, sporadic, extraordinary, seldom, demure, down-to-earth, humble, lowly, meek, unassertive, unpretentious, bashful, mousy, retiring, shy, timid, timorous, diffident, self-doubting, modest, unassuming.
Examples of usage:
  1. The young man looked about on the familiar scene.
    "Dorian", Nephi Anderson.
  2. Is this revolver familiar to you?
    "32 Caliber", Donald McGibeny.
  3. There is something about your face or voice which seems familiar to me.
    "Mr. Marx's Secret", E. Phillips Oppenheim.