De-sexed is a term used to describe animals that have been sterilized, usually through surgical means. However, there are several other words that can be used as synonyms for de-sexed. Some of these include neutered, spayed, castrated, fixed, altered, and sterilized. These words have similar meanings to de-sexed and are commonly used when referring to animals that have been rendered infertile. Neutered and spayed are typically used to describe the sterilization of dogs and cats, while castrated is more commonly used for animals such as horses and livestock. Fixed, altered, and sterilized are broader terms that can be used for any animal that has been sterilized.